Just finished rewatching season 2. When Khaleesi is looking for her dragons in the House of the Undying there is the scene where she is in the icy throne room and goes to touch the throne but gets distracted by the sound of her dragons and never touches it.
I been saying all along she won't end up on the throne but forgot about that scene. Rewatching just reinforces my prediction.
I also think either Jon or Bran will become the Night King and will end the threat to humanity. Cersei to remain on the throne. Khaleesi to end up dead