There's too many classic kobe games/moments to name, but his legendary duel with Mcgrady where they both went off is up there.
Another classic is when A.I first went to the nuggets and they were playing the Lakers and A.I went off for like 30 or so in the first half and then at the half Kobe said he'll guard A.I. I don't think A.I made 1 basket the entire 2nd half and kobe went off and made like 30.
Same shit with that Mcgrady duel, he started guarding mcgrady in the 4th and kinda slowed him down.
That's always been my #1 argument when debating kobe vs lebron. Half the game is offense and the other half is defense. Kobe was one of the greatest defenders of alltime.