The issue snipes had was really with the writers, director, etc ..All this love between Reynolds and Wesley is kinda funny considering how bad their relationship supposedly was during Blade Trinity. I wouldn't have ever thought that Reynolds would be the one to reach out to Wesley.
Him and Ryan, while they might be a lot better now, there wasn't really a huge issue with him personally. I vaguely remember the studio heads were trying to ice snipes out in favor of Reynolds but that wasn't anything Ryan asked them to do